I'm using various sources for the projections. All lines can be found here at the time of posting.
Sunday 1 PM Slate
Ashton Dulin o33.5 receiving yards -130 (DraftKings): The betting markets are a bit low on Dulin, who will see an expanded role with Michael Pittman (quad) and Alec Pierce (concussion) both out against a below average Jaguars secondary. Dulin is projected closer to 40 yards.
Leonard Fournette u31.5 receiving yards -115 (DraftKings): There's certainly some extra targets to go around in Tampa Bay with Chris Godwin (hamstring) out, but this number is still higher than projections that have him in the 25-26 range.
Bryan Edwards o13.5 receiving yards -110 (BetMGM): Edwards, a 3rd round pick from 2020, operates as the Falcons WR3. Although this is a difficult matchup against the Rams, this number is falling well short of his projections, which is closer to 27 yards. With a game total of 46.5, there should be plenty of offense.
Jacoby Brissett o190.5 passing yards -110 (FanDuel): This number falls well below Brissett's projection of 219.5. His matchup against the Jets isn't the toughest in the world, either.
Trevor Lawrence u0.5 interceptions +125 (PointBet): Lawrence had a decent start to the season from an interception perspective - PFF charted him with just one turnover worthy play on 45 dropbacks. He should dropback a lot less this week -- closer to 35 per projections -- and is facing a Colts defense that has a less than impressive secondary. I'm taking the dog odds, and a general bet that Lawrence has improved over a rookie year filled with interceptions and turnover worthy plays.
Sunday 4PM Slate
Russ Wilson o9.5 rushing yards -110 (DraftKings): This number is falling well short of projections that have him around 15-16 yards. It's likely been bet down after Wilson scrambled just once last week for 2 yards, but I certainly wouldn't expect that trend to continue. Russ may not be the scrambler he once was, but he still has some wheels on him and will take off when needed.
Trey Lance o188.5 passing yards -110 (FanDuel): This number falls well below of Lance's projection of 218. Lance had a tough start to the season, but it was in a damn monsoon. Things will be a lot easier this week against the Seahawks at home.
Cooper Rush o213.5 passing yards -110 (FanDuel): This is the exact bet I love to take, because nobody wants to bet on Cooper Rush. Like it or not, he's projected at 242 yards. It's not the easiest matchup against the Bengals, but we can't turn down this number.
Deebo Samuel u35.5 rushing yards -125 (PointBet): It was clear last week that Samuel absolutely still has his hybrid WR/RB role in the 49ers offense, but it was equally clear that Samuel isn't necessarily thrilled about it. In the offseason, Samuel held out until a reworked contract came, which included incentives for running the football. His argument was essentially "if you're going to make me play two positions, you're going to pay me to play two positions." I don't see risking Samuel as a runner when you're a 10 point favorite against the Seahawks as a necessity to the game plan, and this is reflected in his projections, which are in the low 30s.
Monday Night Football
Kirk Cousins u280.5 passing yards -114 (FanDuel): Granted, this game total is 50.5 and should therefore be high scoring. This number is still too high, Cousins is projected around 268.